| 產(chǎn)品編號 | bs-14381R |
| 英文名稱 | DNAJC14 Rabbit pAb |
| 中文名稱 | DNAJC14蛋白抗體 |
| 別 名 | DJC14_HUMAN; DnaJ(Hsp40) homolog, subfamily C, member 14; DNAJ; DnaJ homolog subfamily C member 14; DnaJ protein homolog 3; DNAJC14; Dopamine receptor interacting protein; Dopamine receptor-interacting protein of 78 kDa; DRiP78; hDj 3; HDJ-3; HDJ3; Human DnaJ protein 3; LIP6; LYST interacting protein LIP6. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 細(xì)菌及病毒 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 79 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DNAJC14: 151-250/702 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC14 (DnaJ homolog subfamily C member 14), also known as DRIP78 (Dopamine receptor-interacting protein of 78 kDa) and HDJ3 (Human DnaJ protein 3), is a 702 amino acid endoplasmic reticulular membrane protein that contains one J domain. DnaJC14 regulates the export of target proteins, such as the dopamine D1 receptor (D1DR), from the endoplasmic reticulum to the cell surface. Function: Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney. Similarity: Contains 1 J domain. SWISS: Q6Y2X3 Gene ID: 85406 Database links: Entrez Gene: 85406 Human Entrez Gene: 74330 Mouse Omim: 606092 Human SwissProt: Q6Y2X3 Human SwissProt: Q921R4 Mouse Unigene: 709320 Human Unigene: 296915 Mouse Unigene: 114340 Rat |
