| 產(chǎn)品編號 | bs-17662R |
| 英文名稱 | SPHKAP Rabbit pAb |
| 中文名稱 | 鞘氨醇激酶1相互作用蛋白抗體 |
| 別 名 | A-kinase anchor protein SPHKAP; DKFZp781H143; DKFZp781J171; KIAA1678; MGC132614; MGC132616; SKIP; Sphingosine kinase type 1-interacting protein; SPHK1(sphingosine kinase type 1) interacting protein; SPHK1 interactor, AKAP domain containing; ; SPHK1-interacting protein; SPHK1-interactor and AKAP domain-containing protein; sphkap; SPKAP_HUMAN. |
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Specific References (1) | bs-17662R has been referenced in 1 publications.
[IF=4.183] Zhu Y et al. Protein Expression Profile in Rat Silicosis Model Reveals Upregulation of PTPN2 and Its Inhibitory Effect on Epithelial-Mesenchymal Transition by Dephosphorylation of STAT3. Int J Mol Sci. 2020 Feb 11;21(4). WB ; Rat&Mouse.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 186 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SPHKAP: 1131-1230/1700 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. Subunit: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments. May act as a converging factor linking cAMP and sphingosine signaling pathways. Plays a regulatory role in the modulation of SPHK1. Subcellular Location: Cytoplasm. Colocalizes with SPHK1 in the cytoplasm. Tissue Specificity: Highly expressed in heart. Both isoforms abundantly expressed in ventricle. Also expressed in spleen, ovary and brain. Similarity: Belongs to the AKAP110 family. SWISS: Q2M3C7 Gene ID: 80309 Database links: Entrez Gene: 80309 Human Entrez Gene: 77629 Mouse Omim: 611646 Human SwissProt: Q2M3C7 Human SwissProt: Q6NSW3 Mouse Unigene: 436306 Human Unigene: 154303 Mouse |
