| 產(chǎn)品編號 | bsm-61003R |
| 英文名稱 | RAIDD Recombinant Rabbit mAb |
| 中文名稱 | CASP2凋亡相關(guān)蛋白重組兔單抗 |
| 別 名 | CASP2 and RIPK1 domain containing adaptor with death domain; Caspase and RIP adapter with death domain; Caspase and RIP adaptor with death domain; CRADD; CRADD_HUMAN; Death adaptor molecule RAIDD; Death domain containing protein CRADD; Death domain-containing protein CRADD; MGC9163; RIP associated ICH1/CED3 homologous protein with death domain; RIP associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain; RIP-associated protein with a death domain. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 9D15 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | A synthesized peptide derived from human CRADD: 150-199/199 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. Subunit: Interacts with LRDD. Tissue Specificity: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. Similarity: Contains 1 CARD domain. Contains 1 death domain. Database links: Entrez Gene: 8738 Human Entrez Gene: 12905 Mouse Omim: 603454 Human SwissProt: P78560 Human SwissProt: O88843 Mouse Unigene: 38533 Human Unigene: 591016 Human |
| 產(chǎn)品圖片 |
25 ug total protein per lane of various lysates (see on figure) probed with RAIDD monoclonal antibody, unconjugated (bsm-61003R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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