| 產(chǎn)品編號 | bsm-55521R |
| 英文名稱 | Phospho-JNK (T183/Y185) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化氨基末端激酶重組兔單抗 |
| 別 名 | JNK1+JNK2+JNK3; JNK1/2/3; JNK1+2+3; MAPK8; MAPK9; MAPK10; c Jun N terminal kinase 1; c Jun N terminal kinase 2; c Jun N terminal kinase 3; P-JNK0 |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | SB97 |
| 交叉反應 | Human,Mouse,Rat |
| 產(chǎn)品應用 | WB=1: 100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 46/54 kDa |
| 檢測分子量 | 46/54 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated Synthetic phosphopeptide derived from Human JNK(T183/Y185) |
| 亞 型 | IgG |
| 純化方法 | Affinity Purification |
| 緩 沖 液 | PBS with 100 μg/ml BSA,0.15% ProClin300 and 50% glycerol. |
| 保存條件 | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. SWISS: P45983 Gene ID: 5599 絲氨酸/蘇氨酸蛋白激酶參與多種過程，如細胞增殖、分化、遷移、轉化和程序性細胞死亡。細胞外刺激如促炎細胞因子或物理應激刺激應激激活的蛋白激酶/c-Jun N-末端激酶（SAP/JNK）信號通路。應激激活的蛋白激酶/Jun氨基末端激酶SAPK/JNK可有效、優(yōu)先被各種環(huán)境應激被激活，這些應激反應包括紫外線和γ輻射、神經(jīng)酰胺和炎性細胞因子，以及生長因子和GPCR激動劑（在某些情況下）。與其它MAPK一樣，核心信號轉導單元由一個MAPKKK（一般為MEKK1-MEKK4），或一個能磷酸化和激活MKK4/7的混合譜 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
