| 產(chǎn)品編號(hào) | bs-6817R-AP |
| 英文名稱 | Rabbit Anti-MAGEA11/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的黑色素瘤相關(guān)抗原11抗體 |
| 別 名 | Cancer/testis antigen 1.11; cancer/testis antigen family 1, member 11; CT1.11; MAGE 11; MAGE 11 antigen; MAGAB_HUMAN; MAGE11; MAGEA 11; Melanoma antigen family A 11; Melanoma associated antigen 11; MGC10511. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 信號(hào)轉(zhuǎn)導(dǎo) 腫瘤細(xì)胞生物標(biāo)志物 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 48kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGEA11 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: MAGEA11 (Melanoma antigen family A, 11) is a member of the MAGEA gene family. MAGEA proteins are expressed in melanomas and other cancers. MAGEA11 acts as androgen receptor co-regulator increasing androgen receptor activity by modulating the receptors interdomain interaction. Function: Acts as androgen receptor co-regulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Subcellular Location: Nucleus. Cytoplasm. Tissue Specificity: Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 4110 Human Omim: 300344 Human SwissProt: P43364 Human Unigene: 670252 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
