| 產(chǎn)品編號(hào) | bs-4042R-AP |
| 英文名稱(chēng) | Rabbit Anti-Triosephosphate isomerase/AP Conjugated antibody |
| 中文名稱(chēng) | 堿性磷酸酶（AP）標(biāo)記的磷酸丙糖異構(gòu)酶抗體 |
| 別 名 | TIM; TPI 1; TPI; TPI1; Triose phosphate isomerase 1; Triose phosphate isomerase; Triosephosphate isomerase 1; Triosephosphate isomerase; MGC88108; TPIS_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 27kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Triosephosphate isomerase |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq] Subunit: Homodimer. Post-translational modifications: The initiator methionine for isoform 2 is removed. DISEASE: Triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]: Autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection. Note=The disease is caused by mutations affecting the gene represented in this entry. Similarity: Belongs to the triosephosphate isomerase family. Database links: UniProtKB/Swiss-Prot: P60174.3 Entrez Gene: 7167 Human Entrez Gene: 21991 Mouse Omim: 190450 Human SwissProt: P60174 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ????磷酸丙糖異構(gòu)酶（Triose-phosphate isomerase，通常簡(jiǎn)稱(chēng)為T(mén)PI或TIM）是一種能夠催化丙糖磷酸異構(gòu)體在二羥丙酮磷酸和D型甘油醛-3-磷酸之間轉(zhuǎn)換。 ????磷酸丙糖異構(gòu)酶在糖酵解中具有重要作用，對(duì)于有效的能量生成是必不可少的。磷酸丙糖異構(gòu)酶被發(fā)現(xiàn)存在于幾乎所有的生物體，包括哺乳動(dòng)物、昆蟲(chóng)、真菌、植物和大多數(shù)細(xì)菌中。 ????如果人體缺乏磷酸丙糖異構(gòu)酶，會(huì)導(dǎo)致嚴(yán)重的神經(jīng)系統(tǒng)紊亂，該病癥被稱(chēng)為磷酸丙糖異構(gòu)酶缺乏癥。 |
