| 產(chǎn)品編號(hào) | bs-12977R-Gold |
| 英文名稱 | Rabbit Anti-AZI1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的中心體蛋白AZI1抗體 |
| 別 名 | 5 azacytidine induced 1; 5-azacytidine induced 1; 5-azacytidine-induced protein 1; AZ1; Azi; Azi1; AZI1_HUMAN; Centrosomal protein 131 kDa; Centrosomal protein of 131 kDa; Centrosomal protein of 131 kDa; Cep131; Cep131; KIAA1118; OTTMUSP00000004498; Pre-acrosome localization protein 1; RP23 37J21.1. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞類(lèi)型標(biāo)志物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 122kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AZI1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: AZI1 is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on treatment with 5-azacytidine, which is known to lead to the demethylation of genomic DNA. The AZI1 gene is conserved in dog, cow, mouse, rat, chicken, and zebrafish, and exists as two alternatively spliced isoforms. AZI1 contains one IQ domain, and the gene that encodes it maps to human chromosome 17q25.3. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. Function: May play a role in spermatogenesis. Subcellular Location: Cytoplasm > cytoskeleton > centrosome. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 IQ domain. Database links: Entrez Gene: 22994 Human Omim: 613479 Human SwissProt: Q9UPN4 Human Unigene: 514578 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
