| 產(chǎn)品編號(hào) | bs-20417R-APC |
| 英文名稱 | Rabbit Anti-Somatostatin Receptor 5/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的生長(zhǎng)抑素受體5抗體 |
| 別 名 | somatostatin receptor 5; SS5R; Somatostatin receptor subtype 5; Somatostatin receptor type 5; SS 5R; SS5 R; SST R5; SSTR 5; SSTR5; SS-5-R; SS5-R; SS5R; SSR5_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞膜受體 G蛋白偶聯(lián)受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, Rat, (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Somatostatin Receptor 5 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] Function: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Adult pituitary gland, heart, small intestine, adrenal gland, cerebellum and fetal hypothalamus. No expression in fetal or adult kidney, liver, pancreas, uterus, spleen, lung, thyroid or ovary. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 6755 Human Omim: 182455 Human SwissProt: P35346 Human Unigene: 449840 Human Unigene: 728117 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. SSTR5為G-蛋白偶聯(lián)的細(xì)胞膜受體,SSTR5的表達(dá)與腫瘤的分布、發(fā)生和發(fā)展中起重要作用。 |
